Propargyl alcohol → HCID 22314150, Verbindung

Reaktionsgleichung

[CH3:1][C:2]1[S:6][C:5]2[CH:7]=[C:8](OS(C(F)(F)F)(=O)=O)[CH:9]=[CH:10][C:4]=2[C:3]=1[C:19]1[CH:24]=[CH:23][C:22]([C:25]([F:28])([F:27])[F:26])=[CH:21][CH:20]=1.[CH2:29]([OH:32])[C:30]#[CH:31]>>[CH3:1][C:2]1[S:6][C:5]2[CH:7]=[C:8]([C:31]#[C:30][CH2:29][OH:32])[CH:9]=[CH:10][C:4]=2[C:3]=1[C:19]1[CH:24]=[CH:23][C:22]([C:25]([F:26])([F:27])[F:28])=[CH:21][CH:20]=1

Komponenten

Edukt 2

HCID 7859Propargyl alcohol

HCID 86585425HCID 86585425, Verbindung

Produkt 1

HCID 22314150HCID 22314150, Verbindung

Versuchsvorschrift

In analogy to example 13.1, the Trifluoro-methanesulfonic acid 2-methyl-3-(4-trifluoromethyl-phenyl)-benzo[b]thiophen-6-yl ester was reacted with 2-propyn-1-ol to yield the 3-[2-Methyl-3-(4-trifluoromethyl-phenyl)-benzo[b]thiophen-6-yl]-prop-2-yn-1-ol as yellow oil, MS: 346 (M+).

Quellen und Nachweise

ORD-Eintrag: ord-1cb665cde36f43369ef9016c2bb49d3e
Quelldatensatz: uspto-grants-2007_02
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US07173043B2

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