HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-(Tricyclo(3.3.1.1'3,7)dec-1-yl)ethanol → [5-(4-Fluorophenylcarbamoyl)pyrimidin-2-yloxy]acetic acid 2-adamantan-1-yl-ethyl ester
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-(Tricyclo(3.3.1.1'3,7)dec-1-yl)ethanol | HCID 110810 | — |
| Edukt | [5-(4-Fluorophenylcarbamoyl)pyrimidin-2-yloxy]acetic acid | HCID 21087356 | — |
| Produkt | [5-(4-Fluorophenylcarbamoyl)pyrimidin-2-yloxy]acetic acid 2-adamantan-1-yl-ethyl ester | HCID 69522587 | 75% |
Reaktionsschritte
The titled compound was prepared from [5-(4-fluorophenylcarbamoyl)pyrimidin-2-yloxy]acetic acid using 1-adamantaneethanol (27 mg, 0.15 mmol) as the coupling partner. Concentration (no chromatography) yielded 58 mg (75%) of the titled compound. ESI-MS m/z 454 (MH+), 452 (M−H−).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07176310B1 |
| Quelldatensatz | uspto-grants-2007_02 |
| ORD ID | ord-e6c4e900255f4da29ea14e6aeb60ee08 |
| Quellennotiz | uspto-grants-2007_02 |