HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1-(Hydroxymethyl)isoquinoline → Isoquinoline-1-carbaldehyde
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1-(Hydroxymethyl)isoquinoline | HCID 2776247 | — |
| Katalysator | HCID 178418406 | HCID 178418406 | — |
| Lösungsmittel | Chloroform | HCID 6212 | — |
| Produkt | Isoquinoline-1-carbaldehyde | HCID 265306 | 85,1% |
Reaktionsschritte
Isoquinolin-1-yl-methanol (123.7 mg) was dissolved in chloroform (6.2 ml) and then added with manganese dioxide (chemically processed product) (1.24 g), followed by stirring at room temperature for 30 minutes. The reaction solution was filtrated through Celite and the solvent was then distilled off. The residue was dried under vacuum, thereby obtaining the subject compound (103.9 mg) as a brown solid.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07176227B2 |
| Quelldatensatz | uspto-grants-2007_02 |
| ORD ID | ord-08bcf8622f984d33a60644c8f0c66571 |
| Quellennotiz | uspto-grants-2007_02 |