HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Triethylamine → Ave-9488
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Triethylamine | HCID 8471 | — |
| Edukt | 4-Fluorobenzoyl chloride | HCID 67879 | — |
| Edukt | 2-Aminoindan hydrochloride | HCID 122764 | — |
| Lösungsmittel | Tetrahydrofuran | HCID 8028 | — |
| Produkt | Ave-9488 | HCID 10131276 | — |
Reaktionsschritte
43.70 g (258 mol) 2-aminoindane hydrochloride and 53.43 g (528 mmol) triethylamine were added to 250 ml of tetrahydrofuran, 42.89 g (270 mmol) 4-fluorobenzoylchloride were added, and the mixture was stirred for 2 h at RT.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07179839B2 |
| Quelldatensatz | uspto-grants-2007_02 |
| ORD ID | ord-718b7980b122441ab1ee2810010504e8 |
| Quellennotiz | uspto-grants-2007_02 |