HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Indole → 1H-Indole-3-propanoic acid
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Indole | HCID 798 | — |
| Edukt | Acrylic Acid | HCID 6581 | — |
| Lösungsmittel | Acetic Acid | HCID 176 | — |
| Produkt | 1H-Indole-3-propanoic acid | HCID 3744 | — |
Reaktionsschritte
Reaction of indole XXI with acrylic acid in the presence of acetic acid affords the indole-3-propionic acid. Esterification, alkylation of the indole nitrogen, if desired, and trifluoroacetic acid hydrolysis gives rise to indoles of Formula VII in which R is (CH2)mCO2R9, m is 2 and R2 is H or C1 -C3 alkyl. ##STR29##
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04764610 |
| Quelldatensatz | uspto-grants-1988_08 |
| ORD ID | ord-67ea4b0a1462429cbc7a0a109d6d2d88 |
| Quellennotiz | uspto-grants-1988_08 |