2-(1,3-Benzodioxol-5-yloxy)pyridine-3-carboxylic acid → (+)-2-[3-Fluoro-4-({[2-(3-cyano-phenoxy)-pyridine-3-carbonyl]-amino}-methyl)-phenoxy]-propionic acid tert-butyl ester
Reaktionsgleichung
[C:1]([C:3]1[CH:4]=[C:5]([CH:16]=[CH:17][CH:18]=1)[O:6][C:7]1[N:15]=[CH:14][CH:13]=[CH:12][C:8]=1[C:9]([OH:11])=O)#[N:2].[C:19]([O:23][C:24](=[O:37])[CH:25]([O:27][C:28]1[CH:33]=[CH:32][C:31]([CH2:34][NH2:35])=[C:30]([F:36])[CH:29]=1)[CH3:26])([CH3:22])([CH3:21])[CH3:20].O1C2C=CC(OC3N=CC=CC=3C(O)=O)=CC=2OC1.COC(=O)COC1C=CC(CN)=C(F)C=1>>[C:19]([O:23][C:24](=[O:37])[CH:25]([O:27][C:28]1[CH:33]=[CH:32][C:31]([CH2:34][NH:35][C:9]([C:8]2[C:7]([O:6][C:5]3[CH:16]=[CH:17][CH:18]=[C:3]([C:1]#[N:2])[CH:4]=3)=[N:15][CH:14]=[CH:13][CH:12]=2)=[O:11])=[C:30]([F:36])[CH:29]=1)[CH3:26])([CH3:20])([CH3:21])[CH3:22]
