(+/-)-2-[4-({[2-(Benzo[2,1,3]oxadiazol-5-yloxy)-pyridine-3-carbonyl]-amino}-methyl)-3-fluoro-phenoxy]-propionic acid tert-butyl ester → (+/-)-2-[4-({[2-(Benzo[2,1,3]oxadiazol-5-yloxy)-pyridine-3-carbonyl]-amino}-methyl)-3-fluoro-phenoxy]-propionic acid

Beteiligte Stoffe

Reaktionsschritte

(±)-2-[4-({[2-(Benzo[2,1,3]oxadiazol-5-yloxy)-pyridine-3-carbonyl]-amino}-methyl)-3-fluoro- phenoxy]-propionic acid tert-butyl ester (0.17 g, 0.33 mmol) was stirred in formic acid (5 mL) at room temperature 2 hours. Formic acid was removed in vacuo and the product stored over night under high vacuum to afford a white solid (0.12 g, 80% yield).

Herkunft & Nachweise