Reaktionsgleichung
C([O:5][C:6](=[O:35])[CH:7]([O:9][C:10]1[CH:15]=[CH:14][C:13]([CH2:16][NH:17][C:18]([C:20]2[C:21]([O:26][C:27]3[CH:32]=[CH:31][C:30]([F:33])=[CH:29][CH:28]=3)=[N:22][CH:23]=[CH:24][CH:25]=2)=[O:19])=[C:12]([F:34])[CH:11]=1)[CH3:8])(C)(C)C.C(OC(=O)C(OC1C=CC(CNC(C2C(OC3C=CC4=NON=C4C=3)=NC=CC=2)=O)=C(F)C=1)C)(C)(C)C>>[F:34][C:12]1[CH:11]=[C:10]([CH:15]=[CH:14][C:13]=1[CH2:16][NH:17][C:18]([C:20]1[C:21]([O:26][C:27]2[CH:32]=[CH:31][C:30]([F:33])=[CH:29][CH:28]=2)=[N:22][CH:23]=[CH:24][CH:25]=1)=[O:19])[O:9][CH:7]([CH3:8])[C:6]([OH:35])=[O:5]Komponenten
3
Edukt 2
Produkt 1
Versuchsvorschrift
The compound of Formula (5.5.4) was prepared in a manner analogous to that described in Example 3, substituting (±)-2-[3-fluoro-4-({[2-(4-fluoro-phenoxy)-pyridine-3-carbonyl]-amino}-methyl) -phenoxy]-propionic acid tert-butyl ester for the corresponding (±)-2-[4-({[2-(benzo[2,1,3]oxadiazol-5-yloxy)-pyridine-3-carbonyl]-amino}-methyl)-3-fluoro-phenoxy]-propionic acid tert-butyl ester material.
Quellen und Nachweise
- ORD-Eintrag
- ord-cd821a01e7dd4ce4afd36888aa6ef76a
- Quelldatensatz
- uspto-grants-2007_02
- Patentnummer
- US07183293B2
Verknüpfte Notizen
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