HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Acetoacetic Acid → Atorvastatin lactone
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Acetoacetic Acid | HCID 96 | — |
| Edukt | Ethyl Acetoacetate | HCID 8868 | — |
| Edukt | 7-[2-(4-Fluorophenyl)-5-isopropyl-3-phenyl-4-phenylcarbamoyl-pyrrol-1-yl]-3,5-dioxo-heptanoic acid, ethyl ester | HCID 11330705 | — |
| Produkt | Atorvastatin lactone | HCID 6483036 | — |
Reaktionsschritte
In a process analogous to Step 5 METHOD A, by substituting the appropriate ester or amide of acetoacetic acid for ethyl acetoacetate, one obtains the following compounds:
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07183408B2 |
| Quelldatensatz | uspto-grants-2007_02 |
| ORD ID | ord-366f902b373f4b91ab431912b2e6de22 |
| Quellennotiz | uspto-grants-2007_02 |