HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 35146Erstellt: 23. Oktober 2026
Potassium Carbonate → Diethyl-2-[4'-(4"-cyano-phenoxy)-phenoxy]-propionyl-malonate
https://huagongshe.com/de/reaction/35146
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|
| Edukt | Potassium Carbonate | HCID 11430 | — |
| Edukt | 2-Hydroxybenzonitrile | HCID 11907 | — |
| Edukt | Diethyl-2-(4'-fluoro-phenoxy)-propionyl-malonate | HCID 23037018 | — |
| Lösungsmittel | Dimethyl Sulfoxide | HCID 679 | — |
| Produkt | Diethyl-2-[4'-(4"-cyano-phenoxy)-phenoxy]-propionyl-malonate | HCID 21295006 | 86% |
Reaktionsschritte
11.9 g of cyano-phenol and 32.6 g of diethyl-2-(4'-fluoro-phenoxy)-propionyl-malonate are dissolved in 150 ml of dimethyl sulfoxide, whereupon 13.8 g of potassium carbonate are added and the reaction mixture is stirred at 60° C. for 6 hours. The reaction mixture is filtered and the filtrate is evaporated. Thus 36 g of the desired compound are obtained, yield 86%.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patentnummer | US04765825 |
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| Quelldatensatz | uspto-grants-1988_08 |
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| ORD ID | ord-39eba38794a340b28f97b842753e7fc2 |
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| Quellennotiz | uspto-grants-1988_08 |
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