Ethyl methanesulfonylacetate → Ethyl 3-dimethylamino-2-methylsulphonylacrylate

HRID 351653

Reaktionsgleichung

Reaktionsgleichung von HRID 351653
[CH3:1][S:2]([CH2:5][C:6]([O:8][CH2:9][CH3:10])=[O:7])(=[O:4])=[O:3].CO[CH:13](OC)[N:14]([CH3:16])[CH3:15]>>[CH3:13][N:14]([CH3:16])[CH:15]=[C:5]([S:2]([CH3:1])(=[O:4])=[O:3])[C:6]([O:8][CH2:9][CH3:10])=[O:7]

Komponenten

3

Edukt 2

HCID 78201Ethyl methanesulfonylacetateHCID 78373Dimethylformamide dimethyl acetal

Produkt 1

HCID 57126670Ethyl 3-dimethylamino-2-methylsulphonylacrylate

Reaktionsbedingungen

Temperatur
85 °C

Versuchsvorschrift

6.65 g (40 mmol) of ethyl methanesulphonylacetate and 5.72 g (48 mmol) of N,N-dimethylformamide dimethyl acetal are admixed and heated at 85° C. overnight. The solution is concentrated using a rotary evaporator, and the solid is comminuted with cyclohexane and filtered off with suction.

Aufarbeitung

  1. concentrationThe solution is concentrated
  2. customa rotary evaporator
  3. customthe solid is comminuted with cyclohexane
  4. filtrationfiltered off with suction

Quellen und Nachweise

ORD-Eintrag
ord-d5b98d3c965f4e9796d425aac5851886
Quelldatensatz
uspto-grants-2004_06
Patentnummer
US06743798B1

Verknüpfte Notizen

Wird geladen…