Sodium Hydroxide → 3,4-Dihydro-2H-1,4-benzoxazine

HRID 35178

Reaktionsgleichung

Reaktionsgleichung von HRID 35178
O=[C:2]1[NH:7][C:6]2[CH:8]=[CH:9][CH:10]=[CH:11][C:5]=2[O:4][CH2:3]1.B#B.[OH-].[Na+]>O1CCCC1>[O:4]1[C:5]2[CH:11]=[CH:10][CH:9]=[CH:8][C:6]=2[NH:7][CH2:2][CH2:3]1

Komponenten

5

Edukt 3

HCID 14798Sodium HydroxideHCID 727572H-1,4-benzoxazin-3(4H)-oneHCID 6328200Diboron

Produkt 1

HCID 5850963,4-Dihydro-2H-1,4-benzoxazine

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 8028TetrahydrofuranLösungsmittel

Versuchsvorschrift

3,4-Dihydro-3-oxo-1,4(2H)-benzoxazine was refluxed for several hours in one equivalent of diborane in tetrahydrofuran. Excess sodium hydroxide solution was added, the product was extracted with ether and the solvent was evaporated to give the title compound as an oil.

Aufarbeitung

  1. extractionthe product was extracted with ether
  2. customthe solvent was evaporated

Quellen und Nachweise

ORD-Eintrag
ord-4e559cf6b812488bb588a627a636cd16
Quelldatensatz
uspto-grants-1988_08
Patentnummer
US04766118

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