HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Taurine → 3,5-Dichloro-2-fluoro-4-(3-isopropyl-4-hydroxyphenoxy)-6-(2-hydroxysulfonylethylamino)pyridine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Taurine | HCID 1123 | — |
| Edukt | 3,5-Dichloro-2-fluoro-4-(3-isopropyl-4-methoxyphenoxy)-6-methoxycarbonylmethylamino-pyridine | HCID 9888184 | — |
| Produkt | 3,5-Dichloro-2-fluoro-4-(3-isopropyl-4-hydroxyphenoxy)-6-(2-hydroxysulfonylethylamino)pyridine | HCID 22712113 | — |
Reaktionsschritte
By use of 2-aminoethylsulfonic acid in place of glycine methyl ester for the preparation of Compound 1e followed by deprotection as described for example 2.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06747048B2 |
| Quelldatensatz | uspto-grants-2004_06 |
| ORD ID | ord-0c10dec69a284944882e38c2d9a60f2f |
| Quellennotiz | uspto-grants-2004_06 |