Ethyl α-(acetylamino)-6-quinolinepropanoate → HCID 21925070, Verbindung

HRID 352690Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 352690
C([O:3][C:4](=[O:21])[CH:5]([CH2:10][C:11]1[CH:12]=[C:13]2[C:18](=[CH:19][CH:20]=1)[N:17]=[CH:16][CH:15]=[CH:14]2)[NH:6]C(=O)C)C>Cl>[N:17]1[C:18]2[C:13](=[CH:12][C:11]([CH2:10][CH:5]([C:4]([OH:21])=[O:3])[NH2:6])=[CH:20][CH:19]=2)[CH:14]=[CH:15][CH:16]=1

Komponenten

3

Edukt 1

HCID 21925091Ethyl α-(acetylamino)-6-quinolinepropanoate

Produkt 1

HCID 21925070HCID 21925070, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 313Hydrochloric AcidLösungsmittel

Versuchsvorschrift

N-Acetyl β-(6-quinolinyl)-D,L-alanine ethyl ester (728 mg, 2.55 mmol) was heated at reflux in 6N HCl (20 mL). After 20 h, the reaction mixture was concentrated to dryness and the residue was dried in vacuo to provide the title compound, which was used directly in the next reaction.

Aufarbeitung

  1. concentrationthe reaction mixture was concentrated to dryness
  2. customthe residue was dried in vacuo

Quellen und Nachweise

ORD-Eintrag
ord-2aa6ff3fa1a44ad5bea4052cf34415a6
Quelldatensatz
uspto-grants-2004_06
Patentnummer
US06747150B2

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