HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
L-Hydroxyproline → 1-(Phenylmethyl) (2S,4R)-4-hydroxy-1,2-pyrrolidinedicarboxylate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | L-Hydroxyproline | HCID 5810 | — |
| Edukt | Benzyl chloroformate | HCID 10387 | — |
| Produkt | 1-(Phenylmethyl) (2S,4R)-4-hydroxy-1,2-pyrrolidinedicarboxylate | HCID 391517 | 58% |
Reaktionsschritte
According to the literature procedure (J. Am. Chem. Soc. 189 (1957)), trans-4-hydroxy-L-proline (5.12 g, 0.039 mol) was treated with benzyl chloroformate (8.5 mL, 0.06 mol) to provide the title compound (6.0 g) as a white solid.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06747150B2 |
| Quelldatensatz | uspto-grants-2004_06 |
| ORD ID | ord-ef7a14e3470d461fb1641c7dd5af6295 |
| Quellennotiz | uspto-grants-2004_06 |