1-Hydroxybenzotriazole → 2-(N-Methylcarbamoyl)-1-[(6-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]-4-[(6-trimethylsilylethynylbenzo[b]thien-2-yl)sulfonyl]piperazine

Reaktionsgleichung

[CH3:1][NH:2][C:3]([CH:5]1[NH:10][CH2:9][CH2:8][N:7]([S:11]([C:14]2[S:18][C:17]3[CH:19]=[C:20]([C:23]#[C:24][Si:25]([CH3:28])([CH3:27])[CH3:26])[CH:21]=[CH:22][C:16]=3[CH:15]=2)(=[O:13])=[O:12])[CH2:6]1)=[O:4].[CH3:29][CH:30]1[NH:35][CH2:34][C:33]2[S:36][C:37]([C:39]([O-])=[O:40])=[N:38][C:32]=2[CH2:31]1.[Li+].Cl.C(N=C=NCCCN(C)C)C.ON1C2C=CC=CC=2N=N1>CN(C)C=O.C(Cl)Cl>[CH3:1][NH:2][C:3]([CH:5]1[CH2:6][N:7]([S:11]([C:14]2[S:18][C:17]3[CH:19]=[C:20]([C:23]#[C:24][Si:25]([CH3:26])([CH3:28])[CH3:27])[CH:21]=[CH:22][C:16]=3[CH:15]=2)(=[O:13])=[O:12])[CH2:8][CH2:9][N:10]1[C:39]([C:37]1[S:36][C:33]2[CH2:34][NH:35][CH:30]([CH3:29])[CH2:31][C:32]=2[N:38]=1)=[O:40])=[O:4]