Cyclohexaneacetic acid → Cyclohexylacetyl chloride

HRID 35372

Reaktionsgleichung

Reaktionsgleichung von HRID 35372
[CH:1]1([CH2:7][C:8]([OH:10])=O)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.O=S(Cl)[Cl:13]>>[CH:1]1([CH2:7][C:8]([Cl:13])=[O:10])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

Komponenten

3

Edukt 2

HCID 21363Cyclohexaneacetic acidHCID 24386Thionyl Chloride

Produkt 1

HCID 2757989Cyclohexylacetyl chloride

Versuchsvorschrift

Cyclohexyl acetic acid (2.5 g; 0.02 moles) was mixed with SOCl2 (3.7 cc; 0.05 moles) and the resulting solution was kept at 80° C. for 1.5 hours. The mixture was concentrated under vacuum and some washings were carried out with anhydrous toluene to remove SOCl2. The mixture was then dried under vacuum and the title product was obtained as a raw material which was used as such in the next step (b).

Aufarbeitung

  1. concentrationThe mixture was concentrated under vacuum
  2. customto remove SOCl2
  3. customThe mixture was then dried under vacuum

Quellen und Nachweise

ORD-Eintrag
ord-469fa4391bba411b95e3dae68edade96
Quelldatensatz
uspto-grants-1988_08
Patentnummer
US04766222

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