Cadaverine → N-(5-Aminopentyl)benzamide

HRID 353818

Reaktionsgleichung

Reaktionsgleichung von HRID 353818
[NH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][NH2:7].[C:8](N)(=[O:15])[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1>>[NH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][NH:7][C:8](=[O:15])[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1

Komponenten

3

Edukt 2

HCID 273CadaverineHCID 2331Benzamide

Produkt 1

HCID 345353N-(5-Aminopentyl)benzamideAusbeute 70,6 %

Versuchsvorschrift

Under an argon atmosphere, 1,5-diaminopentane (25 g, 0.24 mol) and benzamide (9.9 g, 0.081 mol) were combined and heated at reflux overnight. The reaction mixture was concentrated under vacuum to remove the excess diamine. The residue was distilled at about 210° C. at 12 torr (16×102 pascals) to provide 11.8 g of N-(5-aminopentyl)benzamide as a colorless oil.

Aufarbeitung

  1. temperatureheated
  2. temperatureat reflux overnight
  3. concentrationThe reaction mixture was concentrated under vacuum
  4. customto remove the excess diamine
  5. distillationThe residue was distilled at about 210° C. at 12 torr (16×102 pascals)

Quellen und Nachweise

ORD-Eintrag
ord-b381b192013040f686acf978ecc3b618
Quelldatensatz
uspto-grants-2004_06
Patentnummer
US06756382B2

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