HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Triethylorthoaceate → N1-[3-(2-methyl-1H-imidazo[4,5-c]quinolin-1-yl)propyl]benzamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Triethylorthoaceate | HCID 21875354 | — |
| Edukt | N1-{3-[(3-nitroquinolin-4-yl)amino]propyl}benzamide | HCID 23512704 | — |
| Produkt | N1-[3-(2-methyl-1H-imidazo[4,5-c]quinolin-1-yl)propyl]benzamide | HCID 23512664 | — |
Reaktionsschritte
Using the general method of Example 11 Part C, N1-{3-[(3-nitroquinolin-4-yl)amino]propyl}benzamide (2.0 g, 5.7 mmol) was reduced to the diamine and then reacted with triethylorthoacetate to provide 0.74 g of N1-[3-(2-methyl-1H-imidazo[4,5-c]quinolin-1-yl)propyl]benzamide as a sticky dark yellow solid.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06756382B2 |
| Quelldatensatz | uspto-grants-2004_06 |
| ORD ID | ord-0f6a1ca1f4e4404a9c5b5a91220b0345 |
| Quellennotiz | uspto-grants-2004_06 |