N-Methylol-alpha-chloroacetamide → 2-Chloro-N-[5-(1,1-dimethylethyl)-3-dimethylaminomethyleneaminosulfonyl-2-hydroxybenzyl]-acetamide

HRID 35397

Reaktionsgleichung

Reaktionsgleichung von HRID 35397
[CH3:1][C:2]([C:5]1[CH:10]=[CH:9][C:8]([OH:11])=[C:7]([S:12]([N:15]=[CH:16][N:17]([CH3:19])[CH3:18])(=[O:14])=[O:13])[CH:6]=1)([CH3:4])[CH3:3].[Cl:20][CH2:21][C:22]([NH:24][CH2:25]O)=[O:23]>S(=O)(=O)(O)O>[Cl:20][CH2:21][C:22]([NH:24][CH2:25][C:9]1[CH:10]=[C:5]([C:2]([CH3:1])([CH3:3])[CH3:4])[CH:6]=[C:7]([S:12]([N:15]=[CH:16][N:17]([CH3:19])[CH3:18])(=[O:13])=[O:14])[C:8]=1[OH:11])=[O:23]

Komponenten

4

Edukt 2

HCID 62466N-Methylol-alpha-chloroacetamideHCID 541555634-(1,1-Dimethylethyl)-2-dimethylaminomethyleneaminosulfonylphenol

Produkt 1

HCID 539481172-Chloro-N-[5-(1,1-dimethylethyl)-3-dimethylaminomethyleneaminosulfonyl-2-hydroxybenzyl]-acetamide

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 1118Sulfuric AcidLösungsmittel

Versuchsvorschrift

3 g (0.01 mole) of 4-(1,1-dimethylethyl)-2-dimethylaminomethyleneaminosulfonylphenol are dissolved in 30 ml of sulfuric acid, and 1.1 g (0.009 mole) of 2-chloro-N-hydroxymethylacetamide are added. The mixture is stirred for 30 minutes at room temperature and poured into ice water. The product is filtered off with suction and recrystallized from methanol.

Aufarbeitung

  1. filtrationThe product is filtered off with suction
  2. customrecrystallized from methanol

Quellen und Nachweise

ORD-Eintrag
ord-aef4cd9e4021414984007a97f385e38f
Quelldatensatz
uspto-grants-1988_08
Patentnummer
US04766241

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