HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Sodium Hydroxide → 7-(1-Phenyl-3-dimethylaminopropoxy)-isoflavone
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Sodium Hydroxide | HCID 14798 | — |
| Edukt | 7-Hydroxyisoflavone | HCID 5376891 | — |
| Edukt | 3-Chloro-N,N-dimethyl-3-phenylpropan-1-amine | HCID 12707239 | — |
| Katalysator | Benzyl triethylammonium chloride | HCID 66133 | — |
| Lösungsmittel | Dichloromethane | HCID 6344 | — |
| Produkt | 7-(1-Phenyl-3-dimethylaminopropoxy)-isoflavone | HCID 12918914 | — |
Reaktionsschritte
200 ml of 50% aqueous sodium hydroxide solution and 1 g of triethylbenzylammonium chloride are added to a solution of 23.8 g of 7-hydroxyisoflavone in 100 ml of CH2Cl2, 20 g of 1-chloro-1-phenyl-3-dimethylaminopropane is added dropwise while stirring and stirring is continued for a further hour. Working up in the customary manner gives 7-(1-phenyl-3-dimethylaminopropoxy)-isoflavone. M.p. 128°-130°.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04376123 |
| Quelldatensatz | uspto-grants-1983_03 |
| ORD ID | ord-957aebb54e1c4efe86a45ceab91bbc5f |
| Quellennotiz | uspto-grants-1983_03 |