HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
N-1,4-Benzodioxane-2-carbonyl piperazine → 2-[4-(1,4-Benzodioxan-2-carbonyl)piperazin-1-yl]-4-amino-6-chloro-7-methoxyquinazoline hydrochloride
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | N-1,4-Benzodioxane-2-carbonyl piperazine | HCID 2735449 | — |
| Edukt | 2,6-Dichloro-7-methoxyquinazolin-4-amine | HCID 12920007 | — |
| Lösungsmittel | Methyl Isobutyl Ketone | HCID 7909 | — |
| Produkt | 2-[4-(1,4-Benzodioxan-2-carbonyl)piperazin-1-yl]-4-amino-6-chloro-7-methoxyquinazoline hydrochloride | HCID 20506410 | — |
Reaktionsschritte
The title compound was prepared by the procedure of Part A, above, by refluxing 2,6-dichloro-4-amino-7-methoxyquinazoline and N-(1,4-benzodioxan-2-carbonyl)-piperazine in methylisobutylketone, M.P. 194°-196° C.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04377581 |
| Quelldatensatz | uspto-grants-1983_03 |
| ORD ID | ord-3c9c88c4157d4988a07ec53cf30076d1 |
| Quellennotiz | uspto-grants-1983_03 |