HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Sodium hydride → 11-(2-Oxo-3-phenyl-benzimidazolin-1-yl)-undecanoic acid methyl ester
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Sodium hydride | HCID 24758 | — |
| Edukt | 2H-Benzimidazol-2-one, 1,3-dihydro-1-phenyl- | HCID 84657 | — |
| Edukt | Methyl 11-bromoundecanoate | HCID 223913 | — |
| Lösungsmittel | Dimethylformamide | HCID 6228 | — |
| Produkt | 11-(2-Oxo-3-phenyl-benzimidazolin-1-yl)-undecanoic acid methyl ester | HCID 12961187 | — |
Reaktionsschritte
The product is produced as described in example 1 from 1.3 g. of NaH (80% suspension in mineral oil), 10 g. of 1-phenylbenzimidazolin-2-one, 200 cc. of DMF, 13.3 g. of 11-bromoundecanoic acid methyl ester and 1.3 g. of NaJ. Eluant in chromatographic purification: hexane/ethylacetate.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04377695 |
| Quelldatensatz | uspto-grants-1983_03 |
| ORD ID | ord-133a1494065746b1ad3399c84cba163e |
| Quellennotiz | uspto-grants-1983_03 |