1H-Indole, 2-propyl- → HCID 54027974, Verbindung

HRID 355150

Reaktionsgleichung

Reaktionsgleichung von HRID 355150
ClC1C=C2C(C([CH:17]([CH2:21][C:22]([C:24]3[C:32]4[C:27](=[CH:28][C:29](Cl)=[CH:30][CH:31]=4)[NH:26][C:25]=3[C:34]3C=CC=CC=3)=O)[C:18]([OH:20])=[O:19])=C(C3C=CC=CC=3)N2)=CC=1.[CH2:40]([C:43]1[NH:44][C:45]2[C:50]([CH:51]=1)=[CH:49][CH:48]=[CH:47][CH:46]=2)CC.[CH2:52]([N:54]1[C:62]2[C:57](=[CH:58][CH:59]=[CH:60][CH:61]=2)[CH:56]=[C:55]1[CH3:63])[CH3:53]>>[CH2:18]([N:44]1[C:45]2[C:50](=[CH:49][CH:48]=[CH:47][CH:46]=2)[C:51]([C:17]2[C:18](=[O:19])[O:20][C:22]([C:24]3[C:32]4[C:27](=[CH:28][CH:29]=[CH:30][CH:31]=4)[N:26]([CH2:22][CH2:24][CH3:25])[C:25]=3[CH3:34])([C:56]3[C:57]4[C:62](=[CH:61][CH:60]=[CH:59][CH:58]=4)[N:54]([CH2:52][CH3:53])[C:55]=3[CH3:63])[CH:21]=2)=[C:43]1[CH3:40])[CH2:17][CH3:21]

Komponenten

4

Edukt 3

HCID 1394151H-Indole, 2-propyl-HCID 1704321H-Indole, 1-ethyl-2-methyl-HCID 204427412,4-Bis(6-chloro-2-phenyl-3-indolyl)-4-oxobutanoic acid

Produkt 1

HCID 54027974HCID 54027974, Verbindung

Versuchsvorschrift

Following a procedure similar to that described above in part B of this example by using 2,4-bis(6-chloro-2-phenyl-3-indolyl)-4-oxobutanoic acid instead of 2,4-bis(1-n-propyl-2-methyl-3-indolyl)-4-oxobutanoic acid, and 2-propylindole is substituted for 1-ethyl-2-methylindole, there is obtained 3,5-bis-(6-chloro-2-phenyl-3-indolyl)-5-(2-propyl-3-indolyl-2(5H)-furanone (Formula III: R=R2 =Y1 =H; R1 =C6H5 ; R3 =CH3CH2CH2 ; Y=6-Cl).

Quellen und Nachweise

ORD-Eintrag
ord-d15e1b9e5a1a45ba84b6984ddf7a6f38
Quelldatensatz
uspto-grants-1983_03
Patentnummer
US04377698

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