3-Isocyanatopyridine → 5-Trifluoromethyl-1-(3-pyridylcarbamoyl)indoline
Reaktionsgleichung
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([N:7]=[C:8]=[O:9])[CH:2]=1.[F:10][C:11]([F:22])([F:21])[C:12]1[CH:13]=[C:14]2[C:18](=[CH:19][CH:20]=1)[NH:17][CH2:16][CH2:15]2>>[F:22][C:11]([F:10])([F:21])[C:12]1[CH:13]=[C:14]2[C:18](=[CH:19][CH:20]=1)[N:17]([C:8](=[O:9])[NH:7][C:3]1[CH:2]=[N:1][CH:6]=[CH:5][CH:4]=1)[CH2:16][CH2:15]2Komponenten
3
Versuchsvorschrift
The title compound was prepared as in the method of (Example 2) from 3-pyridylisocyanate and 5-trifluoromethylindoline (D43) to give (E22) (0.12 g, 38%) m.p. 188°-189° C.
Aufarbeitung
- customto give (E22) (0.12 g, 38%) m.p. 188°-189° C.
Quellen und Nachweise
- ORD-Eintrag
- ord-9fcc26080b174b868f942b230ddbfcd1
- Quelldatensatz
- uspto-grants-1998_11
- Patentnummer
- US05834494
Notizen zur Reaktion
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