4-Chloroaniline → 4-Chloro-N-[(1H-imidazol-2-yl)methyl]aniline
Reaktionsgleichung
[Cl:1][C:2]1[CH:8]=[CH:7][C:5]([NH2:6])=[CH:4][CH:3]=1.[NH:9]1[CH:13]=[CH:12][N:11]=[C:10]1[CH:14]=O>>[Cl:1][C:2]1[CH:8]=[CH:7][C:5]([NH:6][CH2:14][C:10]2[NH:9][CH:13]=[CH:12][N:11]=2)=[CH:4][CH:3]=1Komponenten
3
Versuchsvorschrift
The title compound was prepared from 4-chloroaniline and 2-imidazole-carboxaldehyde by the same procedure as described in Example 24, part A. The residue was crystallized from ethyl acetate to afford the title compound (1.56 g, 72%) as an off white solid.
Aufarbeitung
- customThe residue was crystallized from ethyl acetate
Quellen und Nachweise
- ORD-Eintrag
- ord-686b47919246456c9585f37f18fabb82
- Quelldatensatz
- uspto-grants-1998_11
- Patentnummer
- US05837702
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