Hydrochloric Acid → 5-(Ethylthiomethylene)-3-[4-(imidazo[1,2-a]pyridin-5-ylthio)butyl]thiazolidine-2,4-dione hydrochloride

HRID 357158Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 357158
[CH2:1]([S:3][CH:4]=[C:5]1[S:9][C:8](=[O:10])[N:7]([CH2:11][CH2:12][CH2:13][CH2:14][S:15][C:16]2[N:21]3[CH:22]=[CH:23][N:24]=[C:20]3[CH:19]=[CH:18][CH:17]=2)[C:6]1=[O:25])[CH3:2].[ClH:26]>CO>[ClH:26].[CH2:1]([S:3][CH:4]=[C:5]1[S:9][C:8](=[O:10])[N:7]([CH2:11][CH2:12][CH2:13][CH2:14][S:15][C:16]2[N:21]3[CH:22]=[CH:23][N:24]=[C:20]3[CH:19]=[CH:18][CH:17]=2)[C:6]1=[O:25])[CH3:2]

Komponenten

4

Edukt 2

HCID 313Hydrochloric AcidHCID 541990195-(Ethylthiomethylene)-3-[4-(imidazo[1,2-a]pyridin-5-ylthio)butyl]thiazolidine-2,4-dione

Produkt 1

HCID 734729115-(Ethylthiomethylene)-3-[4-(imidazo[1,2-a]pyridin-5-ylthio)butyl]thiazolidine-2,4-dione hydrochloride

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 887MethanolLösungsmittel

Versuchsvorschrift

To a solution of 0.76 g (1.93 mmol) of 5-(ethylthiomethylene)-3-[4-(imidazo[1,2-a]pyridin-5-ylthio)butyl]thiazolidine-2,4-dione in 20 ml of methanol, 0.21 ml of concentrated hydrochloric acid was added. After the solvent was distilled off, the residue was washed with diethyl ether to yield 0.78 g (94.0%, yellow solid) of the desired product.

Aufarbeitung

  1. distillationAfter the solvent was distilled off
  2. washthe residue was washed with diethyl ether

Quellen und Nachweise

ORD-Eintrag
ord-be8e65d8d7ac414db4a15bedb9dbc3cf
Quelldatensatz
uspto-grants-1998_11
Patentnummer
US05840732

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