5-(S)-methyl-7-(t-butyldimethylsilyloxy)-2-heptene → (3S)-3-Methylheptan-1-OL

HRID 35723Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 35723
[CH3:1][C@H:2]([CH2:7][CH2:8][O:9][Si](C(C)(C)C)(C)C)[CH2:3][CH:4]=[CH:5][CH3:6].[H][H]>[OH-].[OH-].[Pd+2].CO>[CH3:1][C@@H:2]([CH2:3][CH2:4][CH2:5][CH3:6])[CH2:7][CH2:8][OH:9]

Komponenten

5

Edukt 2

HCID 537803775-(S)-methyl-7-(t-butyldimethylsilyloxy)-2-hepteneHCID 178418361HCID 178418361, Verbindung

Produkt 1

HCID 12490717(3S)-3-Methylheptan-1-OL

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 9942167Palladium hydroxideKatalysatorHCID 887MethanolLösungsmittel

Versuchsvorschrift

To a solution of 74.8 g. of 5-(S)-methyl-7-(t-butyldimethylsilyloxy)-2-heptene in 500 ml. of methanol was added 7.5 g. of 10% palladium hydroxide on carbon and the mixture shaken in a hydrogen atmosphere for 1.5 hours at 50 psi. The catalyst was filtered and the solvent removed under vacuum, 30 g.

Aufarbeitung

  1. filtrationThe catalyst was filtered
  2. customthe solvent removed under vacuum, 30 g

Quellen und Nachweise

ORD-Eintrag
ord-01daf8a69ff143439ee15aa2712ff87a
Quelldatensatz
uspto-grants-1988_08
Patentnummer
US04767743

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