Methyl 6-aminohexanoate → Caprolactam acetylene
Reaktionsgleichung
[NH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][C:7]([O:9]C)=O>C1(C)C=C(C)C=C(C)C=1>[C:7]1(=[O:9])[NH:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1.[CH:2]#[CH:3]Komponenten
3
Edukt 1
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Reaktionsbedingungen
- Temperatur
- 140 °C
Versuchsvorschrift
A solution of 37.1 g (0.256 mol) of methyl 6-aminocaproate in 723 g of mesitylene is stirred under reflux at 140° C./500 bar for 12 h. Evaporating off the mesitylene under reduced pressure leaves 46.4 g of a caprolactam-acetylene mixture which, according to HPLC, contains 58.2% of caprolactam, which corresponds to 27.0 g (0.239 mol) and a yield of 93.4%.
Aufarbeitung
- customEvaporating off the mesitylene under reduced pressure
Quellen und Nachweise
- ORD-Eintrag
- ord-955be329f2be48739f9d648bd81f7872
- Quelldatensatz
- uspto-grants-1988_08
- Patentnummer
- US04767857
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