Thionyl Chloride → HCID 20064749, Verbindung

HRID 359279Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 359279
[C:1]([NH:5][C:6]1[O:7][C:8]([C:15]([OH:17])=O)=[C:9]([C:11]([F:14])([F:13])[F:12])[N:10]=1)([CH3:4])([CH3:3])[CH3:2].S(Cl)([Cl:20])=O>CN(C)C=O>[CH3:2][C:1]([NH:5][C:6]1[O:7][C:8]([C:15]([Cl:20])=[O:17])=[C:9]([C:11]([F:14])([F:13])[F:12])[N:10]=1)([CH3:4])[CH3:3]

Komponenten

4

Edukt 2

HCID 24386Thionyl ChlorideHCID 15812073HCID 15812073, Verbindung

Produkt 1

HCID 20064749HCID 20064749, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6228DimethylformamideLösungsmittel

Versuchsvorschrift

By the procedure of Example 27, 17 g (64.5 mmol) of 2-(tert-butylamino)-4-trifluoromethyl-5-oxazolecarboxylic acid, 67 ml thionyl chloride and 4 of drops dimethylformamide were reacted together. The product was separated and then distilled to yield 17.2 g of a yellow solid product (m.p.=52°-60° C.; b.p. 70° C. @ 0.25 mm Hg) identified in Table I.

Aufarbeitung

  1. customThe product was separated
  2. distillationdistilled

Quellen und Nachweise

ORD-Eintrag
ord-3f5b19ad54034452bb000a87a1633a77
Quelldatensatz
uspto-grants-1991_03
Patentnummer
US05000775

Notizen zur Reaktion

Wird geladen…