Propylurea → HCID 20064732, Verbindung

HRID 359284

Reaktionsgleichung

Reaktionsgleichung von HRID 359284
[CH2:1]([NH:4][C:5]([NH2:7])=[O:6])[CH2:2][CH3:3].Cl[CH:9]([C:15]([C:17]([F:20])([F:19])[F:18])=O)[C:10]([O:12][CH2:13][CH3:14])=[O:11]>>[CH2:1]([NH:4][C:5]1[O:6][C:9]([C:10]([O:12][CH2:13][CH3:14])=[O:11])=[C:15]([C:17]([F:18])([F:20])[F:19])[N:7]=1)[CH2:2][CH3:3]

Komponenten

3

Edukt 2

HCID 12303PropylureaHCID 2737165Ethyl 2-chloro-4,4,4-trifluoro-3-oxobutanoate

Produkt 1

HCID 20064732HCID 20064732, VerbindungAusbeute 17,3 %

Versuchsvorschrift

By the procedure of Example 4, 6.13 g (60 mmol) of n-propyl urea was reacted with 10.9 g (50 mmol) of ethyl 2-chloro-4,4,4-trifluoroacetoacetate at 140°-150° C. for 18 hours. The product was separated and then recrystallized from n-heptane to yield 2.3 g of a yellow powder product (m.p.=33°-34° C.) identified in Table I.

Aufarbeitung

  1. customThe product was separated
  2. customrecrystallized from n-heptane

Quellen und Nachweise

ORD-Eintrag
ord-d8a766a8b17f4de8b8880790b30fba54
Quelldatensatz
uspto-grants-1991_03
Patentnummer
US05000775

Verknüpfte Notizen

Wird geladen…