HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Pyridine → 3-(Bromomethyl)benzoic acid, 3-(hexadecyloxy)-2-methoxypropyl ester
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Pyridine | HCID 1049 | — |
| Edukt | 1-O-hexadecyl-2-O-methylglycerol | HCID 1380 | — |
| Edukt | 3-(Bromomethyl)benzoyl chloride | HCID 14471076 | — |
| Lösungsmittel | Tetrahydrofuran | HCID 8028 | — |
| Produkt | 3-(Bromomethyl)benzoic acid, 3-(hexadecyloxy)-2-methoxypropyl ester | HCID 57087588 | 78,3% |
Reaktionsschritte
a mixture of 8 g of 3-(hexadecyloxy)-2-methoxypropanol, 6.22 g of m-bromomethylbenzoyl chloride, 2.11 g of pyridine and 80 ml of tetrahydrofuran was stirred for 48 hours, then filtered and evaporated. The residue was purified by chromatography and crystallized giving 10 g of 3-(bromomethyl)benzoic acid, 3-(hexadecyloxy)-2-methoxypropyl ester as white solid.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05411983 |
| Quelldatensatz | uspto-grants-1995_05 |
| ORD ID | ord-e5e0c058700b43d692f14a2aadf27ffa |
| Quellennotiz | uspto-grants-1995_05 |