Benzyl chloroformate → 4''-[2-Butyl-6-(3-isopropyl-3-methyl-ureido)-4-oxo-4H-quinazolin-3-ylmethyl]-biphenyl-2-sulfonic acid benzyloxycarbonylamide(L-162620)

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	Benzyl chloroformate	HCID 10387	—
Edukt	Butyl chloroformate	HCID 61140	—
Edukt	7-methyl-2-propyl-3-[2'-(aminosulfonyl)[1,1']-biphenyl-4-yl]methyl-6-[(1-oxobutyl)amino]-3H-imidazo[4,5-b]pyridine	HCID 19939752	—
Produkt	4''-[2-Butyl-6-(3-isopropyl-3-methyl-ureido)-4-oxo-4H-quinazolin-3-ylmethyl]-biphenyl-2-sulfonic acid benzyloxycarbonylamide(L-162620)	HCID 9917399	—

Reaktionsschritte

The title compound was prepared from 7-methyl-2-propyl-3-[2'-(aminosulfonyl)[1,1']-biphenyl-4-yl]methyl-6-[(1-oxobutyl)amino]-3H-imidazo[4,5-b]pyridine as described in Example 30 substituting the reagent benzyl chloroformate for butyl chloroformate in Step 5. FAB MS for C35H37N5SO5 : M+ +1=640.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US05412097
Quelldatensatz	uspto-grants-1995_05
ORD ID	ord-f126533a13fb404a9768c31baa65791a
Quellennotiz	uspto-grants-1995_05