Sodium Carbonate → 5-Phenyl-2-picoline N-oxide

HRID 363196

Reaktionsgleichung

Reaktionsgleichung von HRID 363196
[C:1]1([C:7]2[CH:8]=[N:9][C:10]([CH3:13])=[CH:11][CH:12]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.C1C=C(Cl)C=C(C(OO)=[O:22])C=1.C([O-])([O-])=O.[Na+].[Na+]>C(Cl)Cl>[C:1]1([C:7]2[CH:8]=[N+:9]([O-:22])[C:10]([CH3:13])=[CH:11][CH:12]=2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Komponenten

5

Edukt 3

HCID 10340Sodium CarbonateHCID 70297m-Chloroperbenzoic acidHCID 767442-Methyl-5-phenylpyridine

Produkt 1

HCID 149805285-Phenyl-2-picoline N-oxide

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel

Versuchsvorschrift

A solution of 3-phenyl-6-methyl pyridine (2.36 g, 13.95 mmol), in CH2Cl2 (40 mL) at 0° C. was treated with MCPBA (3.58 g, 13.95 mmol) for 1 hour. Saturated aq. Na2CO3 (50 mL) was added and the reaction was extracted with CH2Cl2 (20 mL). The organic extracts were dried (MgSO4), and the solvent evaporated in vacuo to afford the title compound.

Aufarbeitung

  1. extractionthe reaction was extracted with CH2Cl2 (20 mL)
  2. dry with materialThe organic extracts were dried (MgSO4)
  3. customthe solvent evaporated in vacuo

Quellen und Nachweise

ORD-Eintrag
ord-05a8840426d74b2e8630c01407e52f00
Quelldatensatz
uspto-grants-1999_02
Patentnummer
US05872136

Verknüpfte Notizen

Wird geladen…