HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Acetic Acid → 1,3-Dihydro-7,8-dimethoxy-2H-3-benzazepin-2-one
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Acetic Acid | HCID 176 | — |
| Edukt | n-(2,2-Dimethoxyethyl)-2-(3,4-dimethoxyphenyl)acetamide | HCID 13092500 | — |
| Lösungsmittel | Hydrochloric Acid | HCID 313 | — |
| Produkt | 1,3-Dihydro-7,8-dimethoxy-2H-3-benzazepin-2-one | HCID 1482373 | — |
Reaktionsschritte
A solution of N-(2,2-dimethoxyethyl)-3,4-dimethoxy-phenylacetamide (600.6 g) in concentrated hydrochloric acid (3 liters) is mixed with glacial acetic acid (3 liters). After being left to stand for 17 hours at ambient temperature and mixture is poured onto ice. The crystals obtained are suction filtered, washed with water until neutral and dried.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04604389 |
| Quelldatensatz | uspto-grants-1986_08 |
| ORD ID | ord-6c570c39b0344cbfbe69dbff20377c7a |
| Quellennotiz | uspto-grants-1986_08 |