HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Methylamine → HCID 178485067, Verbindung
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Methylamine | HCID 6329 | — |
| Edukt | HCID 178503928 | HCID 178503928 | — |
| Lösungsmittel | Ethanol | HCID 702 | — |
| Produkt | HCID 178485067 | HCID 178485067 | — |
Reaktionsschritte
A solution of 4-amino-2-[2-(3-cyano-2-methylisothioureido)ethylthiomethyl]pyrimidine (0.75 g.) in 33% w/v methylamine in ethanol (15 ml.) was left at room temperature for 18 hours. The solution was concentrated to 5 ml., cooled in ice, and the crystalline precipitate collected to give 4-amino-2-[2-(2-cyano-3-methylguanidino)ethylthiomethyl]pyrimidine (0.52 g.), m.p. 189°-190°.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04604465 |
| Quelldatensatz | uspto-grants-1986_08 |
| ORD ID | ord-b4fa69d3d5574b8593f56bc8ccaf3c8b |
| Quellennotiz | uspto-grants-1986_08 |