Acryloyl chloride → N-(2,2-Dimethoxyethyl)-2-propenamide

HRID 364671Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 364671
[C:1](Cl)(=[O:4])[CH:2]=[CH2:3].Cl.[CH3:7][O:8][CH:9]([O:12][CH3:13])[CH2:10][NH2:11]>>[CH3:7][O:8][CH:9]([O:12][CH3:13])[CH2:10][NH:11][C:1](=[O:4])[CH:2]=[CH2:3]

Komponenten

3

Edukt 2

HCID 13140Acryloyl chloride2×HCID 20239692HCID 20239692, Verbindung

Produkt 1

HCID 9898899N-(2,2-Dimethoxyethyl)-2-propenamideAusbeute 92 %

Versuchsvorschrift

The round bottom flask was suspended in a dry ice-isopropanol bath. When the contents reached 0° C., the acryloylchloride solution was allowed to slowly drip into the flask. Temperature was maintained at 0° to 3° C. over a 40 minute period during which all the acryloylchloride solution had been added. Voluminous white crystals of aminoacetaldehyde dimethylacetal hydrochloride were present in the product. These crystals were removed via filtration. Methoxyhydroquinone (0.1 gram) was added and the filtrate was concentrated by evaporation of the ethyl ether to yield 189 grams of N-(2,2 dimethoxyethyl)acrylamide (92% yield).

Aufarbeitung

  1. customThe round bottom flask was suspended in a dry ice-isopropanol bath
  2. customreached 0° C.
  3. additionhad been added
  4. customThese crystals were removed via filtration
  5. additionMethoxyhydroquinone (0.1 gram) was added
  6. concentrationthe filtrate was concentrated by evaporation of the ethyl ether

Quellen und Nachweise

ORD-Eintrag
ord-60364b320b594d9c9b36e88d95f394c0
Quelldatensatz
uspto-grants-1986_08
Patentnummer
US04605718

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