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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 364688Erstellt: 26. Oktober 2026

Acetic Acid → 4-Fluorobenzoic Acid

https://huagongshe.com/reaction/364688

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktAcetic AcidHCID 176—
Eduktp-FluorotolueneHCID 9603—
KatalysatorCobalt(II) acetate tetrahydrateHCID 61372—
KatalysatorSodium BromideHCID 253881—
KatalysatorSodium AcetateHCID 517045—
LösungsmittelWaterHCID 962—
Produkt4-Fluorobenzoic AcidHCID 997386,6%

Reaktionsschritte

The test described in Example 1 was repeated using 300 g of p-fluorotoluene, 660 g of acetic acid, 132 g of water, 6 g of cobalt acetate tetrahydrate, 5 g of sodium bromide and 5 g of sodium acetate. In a reaction time of 240 minutes, after conventional work-up, 330.5 g of p-fluorobenzoic acid (86.6% of the theory) was obtained, with a purity of 99.9%.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS04605757
Quelldatensatzuspto-grants-1986_08
ORD IDord-1fce89aec2444e30b48c457d6650fca9
Quellennotizuspto-grants-1986_08