Chlorosulfonic acid → 5-tert-Butyl-2-methoxybenzene-1-sulfonyl chloride

HRID 364890

Reaktionsgleichung

Reaktionsgleichung von HRID 364890
[CH3:1][C:2]([C:5]1[CH:10]=[CH:9][C:8]([O:11][CH3:12])=[CH:7][CH:6]=1)([CH3:4])[CH3:3].[Cl:13][S:14](O)(=[O:16])=[O:15]>C(Cl)Cl>[CH3:4][C:2]([C:5]1[CH:10]=[C:9]([S:14]([Cl:13])(=[O:16])=[O:15])[C:8]([O:11][CH3:12])=[CH:7][CH:6]=1)([CH3:1])[CH3:3]

Komponenten

4

Edukt 2

HCID 24638Chlorosulfonic acidHCID 94750p-tert-Butylanisole

Produkt 1

HCID 132102315-tert-Butyl-2-methoxybenzene-1-sulfonyl chloride

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel2×

Versuchsvorschrift

12.3 g (0.075 mole) of 4-(1,1-dimethylethyl)anisole, dissolved in 30 ml of methylene chloride, are added dropwise, while cooling with ice, to 16.5 ml of chlorosulfonic acid, dissolved in 20 ml of methylene chloride. The mixture is stirred for 40 minutes and is then poured into ice water. The organic phase is separated off, washed with water, dried with MgSO4 and concentrated.

Aufarbeitung

  1. additionare added dropwise
  2. customThe organic phase is separated off
  3. washwashed with water
  4. dry with materialdried with MgSO4
  5. concentrationconcentrated

Quellen und Nachweise

ORD-Eintrag
ord-9e2e5c0e0d1446c3a6f29477aee1c55f
Quelldatensatz
uspto-grants-1986_08
Patentnummer
US04607030

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