HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 365152Erstellt: 24. Oktober 2026
Potassium Carbonate → 11-{1-[2-(3,4,5-Trimethoxyphenyl)ethyl]piperidin-4-yl}-5H,11H-pyrrolo[2,1-c][1,4]benzoxazepine
https://huagongshe.com/de/reaction/365152
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|
| Edukt | Potassium Carbonate | HCID 11430 | — |
| Edukt | 2-(3,4,5-Trimethoxyphenyl)ethyl methanesulfonate | HCID 11616258 | — |
| Edukt | 11-(piperdin-4-yl)-5H,11H-pyrrolo[2,1-c][1,4]benzoxazepine | HCID 13689358 | — |
| Lösungsmittel | Dimethylformamide | HCID 6228 | — |
| Produkt | 11-{1-[2-(3,4,5-Trimethoxyphenyl)ethyl]piperidin-4-yl}-5H,11H-pyrrolo[2,1-c][1,4]benzoxazepine | HCID 13689405 | — |
Reaktionsschritte
A mixture of 11-(piperidin-4-yl)-5H,11H-pyrrolo[2,1-c][1,4]benzoxazepine (5.8 g, 0.022 mole), K2CO3 (11.0 g) and 2-(3,4,5-trimethoxyphenyl)ethyl methanesulfonate (7.53 g, 0.026 mole) in 120 ml dimethylformamide was heated at 70° C. for 4.5 hours.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patentnummer | US04608374 |
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| Quelldatensatz | uspto-grants-1986_08 |
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| ORD ID | ord-32ab08def0fc4a98914fcd008c84b192 |
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| Quellennotiz | uspto-grants-1986_08 |
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