Methanol → Pyridine-3,5-dicarboxylic acid methyl ester hydrochloride

Beteiligte Stoffe

Reaktionsschritte

Pyridine-3,5-dicarboxylic acid (5.00 g, 29.9 mmol) was stirred in CH3OH (100 mL), cooled in an ice bath, and treated dropwise with thionyl chloride (17.45 mL, 239.2 mmol). After 0.5 hr, the reaction mixture was refluxed for 48 hrs. Concentration to dryness gave the title compound as an off-white solid.

Herkunft & Nachweise