Thionyl Chloride → 3-(3-Pyridyl)acryloyl chloride hydrochloride

HRID 36548

Reaktionsgleichung

Reaktionsgleichung von HRID 36548
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([CH:7]=[CH:8][C:9]([OH:11])=O)[CH:2]=1.S(Cl)([Cl:14])=O>C1C=CC=CC=1>[ClH:14].[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([CH:7]=[CH:8][C:9]([Cl:14])=[O:11])[CH:2]=1

Komponenten

4

Edukt 2

HCID 24386Thionyl ChlorideHCID 1019843-(3-Pyridinyl)-2-propenoic acid

Produkt 1

HCID 713600273-(3-Pyridyl)acryloyl chloride hydrochloride

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 241BenzeneLösungsmittel

Versuchsvorschrift

67 ml of benzene was added to 10 grams of 3-(3-pyridyl)-acrylic acid. 8.1 ml of thionyl chloride was added dropwise slowly thereto at ambient temperature. The temperature was elevated to 70° C. and the heating was continued until foaming ceased. Benzene and thionyl chloride were distilled off and the residue was dried thoroughly under reduced pressure.

Aufarbeitung

  1. customat ambient temperature
  2. customwas elevated to 70° C.
  3. distillationBenzene and thionyl chloride were distilled off
  4. customthe residue was dried thoroughly under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-c47a2810ac0e4dcd8f71084b2669a25f
Quelldatensatz
uspto-grants-1995_05
Patentnummer
US05415780

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