Pyridine → 2-Ethynylphenol

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	Pyridine	HCID 1049	—
Edukt	Benzofuran	HCID 9223	—
Edukt	Sodium	HCID 5360545	—
Lösungsmittel	Water	HCID 962	—
Produkt	2-Ethynylphenol	HCID 138415	54%

Reaktionsschritte

In the process described in Bull. Chem. Soc. Japan 29, 470-1(1956), benzofuran is heat-refluxed in the presence of pyridine and metallic sodium and thereafter treated with water to obtain 2-hydroxyphenylacetylene in 54% yield.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US06127583
Quelldatensatz	uspto-grants-2000_10
ORD ID	ord-4583fc4ca99148e2b79a6e400394a2f8
Quellennotiz	uspto-grants-2000_10