HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Phosphorus oxychloride → 4-Chloro-2-(isoxazol-5-yl)-6-nitro-thieno-[2,3-d]-pyrimidine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Phosphorus oxychloride | HCID 24813 | — |
| Edukt | 3-Thiophenecarboxylic acid, 2-amino-5-nitro-, ethyl ester | HCID 2737608 | — |
| Edukt | 1,2-Oxazole-5-carbonitrile | HCID 11228764 | — |
| Produkt | 4-Chloro-2-(isoxazol-5-yl)-6-nitro-thieno-[2,3-d]-pyrimidine | HCID 18460084 | — |
Reaktionsschritte
With the procedure of Example 477, the reaction of 5-cyanoisoxazole and 2-amino-5-nitro-3-ethoxycarbonyl-thiophene, and the subsequent reaction with POCl3 yields 4-chloro-2-(isoxazol-5-yl)-6-nitro-thieno-[2,3-d]-pyrimidine
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06133271 |
| Quelldatensatz | uspto-grants-2000_10 |
| ORD ID | ord-907e089fca9846559f9af968fdce24a7 |
| Quellennotiz | uspto-grants-2000_10 |