HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Phosphorus oxychloride → 4-Chloro-2-(pyrazin-2-yl)-5,6-dimethyl-thieno-[2,3-d]-pyrimidine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Phosphorus oxychloride | HCID 24813 | — |
| Edukt | Pyrazinecarbonitrile | HCID 73172 | — |
| Edukt | Ethyl 2-amino-4,5-dimethyl3-thenoate | HCID 78536 | — |
| Produkt | 4-Chloro-2-(pyrazin-2-yl)-5,6-dimethyl-thieno-[2,3-d]-pyrimidine | HCID 18460273 | — |
Reaktionsschritte
With the procedure of Example 477, the reaction of 2-cyanopyrazine and 2-amino-4,5-dimethyl-3-ethoxycarbonyl-thiophene, and the subsequent reaction with POCl3 yields 4-chloro-2-(pyrazin-2-yl)-5,6-dimethyl-thieno-[2,3-d]-pyrimidine
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06133271 |
| Quelldatensatz | uspto-grants-2000_10 |
| ORD ID | ord-d549f6b9f1d442af90fe9d64cae76495 |
| Quellennotiz | uspto-grants-2000_10 |