HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-Cyanopyridine → 4-Chloro-2-(pyridin-4-yl)-5-methyl-thieno-[2,3-d]-pyrimidine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4-Cyanopyridine | HCID 7506 | — |
| Edukt | Phosphorus oxychloride | HCID 24813 | — |
| Edukt | Ethyl 2-amino-4-methylthiophene-3-carboxylate | HCID 521132 | — |
| Produkt | 4-Chloro-2-(pyridin-4-yl)-5-methyl-thieno-[2,3-d]-pyrimidine | HCID 18459892 | — |
Reaktionsschritte
With the procedure of Example qq, the reaction of 4-cyanopyridine and 2-amino-4-methyl-3-ethoxycarbonyl-thiophene, and the subsequent reaction with POCl3 yields 4-chloro-2-(pyridin-4-yl)-5-methyl-thieno-[2,3-d]-pyrimidine
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06133271 |
| Quelldatensatz | uspto-grants-2000_10 |
| ORD ID | ord-17b0c4c05b70469f93aaa6776d8607e0 |
| Quellennotiz | uspto-grants-2000_10 |