N,N-diethyl-m-toluamide → N,N-Diethyl-5-methyl-2-(trimethylsilyl)benzamide

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	N,N-diethyl-m-toluamide	HCID 4284	—
Edukt	Chlorotrimethylsilane	HCID 6397	—
Produkt	N,N-Diethyl-5-methyl-2-(trimethylsilyl)benzamide	HCID 18630275	46%

Reaktionsschritte

These compounds were prepared from N,N-diethyl-3-methylbenzamide and 2.0 eq TMSCl according to General Method A. Purification by HPLC using 1:9 ethyl acetate/hexanes gave two products. Compound 63 was isolated as 6.0 g of a clear oil, a 46% yield. Compound 64 was isolated as 2.3 g of a clear oil, a 17% yield.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US06133252
Quelldatensatz	uspto-grants-2000_10
ORD ID	ord-821f8b5598434dcaa2d02e9295f7a63a
Quellennotiz	uspto-grants-2000_10