HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Cytidine → 2'-O-Nonylcytidine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Cytidine | HCID 6175 | — |
| Edukt | 1-Iodononane | HCID 20275 | — |
| Edukt | Sodium hydride | HCID 24758 | — |
| Lösungsmittel | Dimethylformamide | HCID 6228 | — |
| Produkt | 2'-O-Nonylcytidine | HCID 22868393 | — |
Reaktionsschritte
Cytidine (10.1 g, 0.0415 mol), sodium hydride (2.0 g, 1.2 eq), iodononane (9.8 ml, 1.2 eq.) in DMF (100 ml) were reacted as per the procedure of Example 71, Step 1 to yield the 2' and 3' isomers as a sticky foam (11.6 g).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06133438 |
| Quelldatensatz | uspto-grants-2000_10 |
| ORD ID | ord-f45fe0de1f704c428b0d60062018bdb3 |
| Quellennotiz | uspto-grants-2000_10 |