HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Diethylene Glycol Monoethyl Ether → 3-[4-(4-m-Methoxyphenylpiperazino)butyl]indole-5-carboxamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Diethylene Glycol Monoethyl Ether | HCID 8146 | — |
| Edukt | Sodium Hydroxide | HCID 14798 | — |
| Edukt | 3-[4-(4-m-Methoxyphenylpiperazino)butyl]-5-cyanoindole | HCID 19936482 | — |
| Lösungsmittel | Water | HCID 962 | — |
| Produkt | 3-[4-(4-m-Methoxyphenylpiperazino)butyl]indole-5-carboxamide | HCID 19936456 | — |
Reaktionsschritte
A mixture of 30.6 g of 3-[4-(4-m-methoxyphenylpiperazino)butyl]-5-cyanoindole, 27.1 g of NaOH, 520 ml of water and 420 ml of diethylene glycol monoethyl ether is stirred for 3 hours at a bath temperature of 140°. It is cooled and worked up in a conventional manner, and 3-[4-(4-m-methoxyphenylpiperazino)butyl]indole-5-carboxamide is obtained.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05418237 |
| Quelldatensatz | uspto-grants-1995_05 |
| ORD ID | ord-f6566778685e4c7d97edb5d95ee8c66c |
| Quellennotiz | uspto-grants-1995_05 |