4-(1,2,3,4-Tetrahydroquinolin-1-yl)-6-(4-nitro-phenyl)-7H-pyrrolo[2,3-d]-pyrimidine → 4-(1,2,3,4-Tetrahydroquinolin-1-yl)-6-(4amino-phenyl)-7H-pyrrolo[2.3-d]-pyrimidine

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	4-(1,2,3,4-Tetrahydroquinolin-1-yl)-6-(4-nitro-phenyl)-7H-pyrrolo[2,3-d]-pyrimidine	HCID 23282467	—
Katalysator	Nickel	HCID 935	—
Lösungsmittel	Toluene acetone	HCID 20247278	—
Produkt	4-(1,2,3,4-Tetrahydroquinolin-1-yl)-6-(4amino-phenyl)-7H-pyrrolo[2.3-d]-pyrimidine	HCID 9862831	—

Reaktionsschritte

This product is obtained in a manner analogous to that described in Example 7 by hydrogenation of 4-(1,2,3,4-tetrahydroquinolin-1-yl)-6-(4-nitro-phenyl)-7H-pyrrolo[2,3-d]-pyrimidine (Example 10) with Raney nickel. M.p. 243-245° C.; FAB-MS: (M+H)+ =342 (corresponds to C21H19N5); Rf value (toluene-acetone--4:6)=0.25.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US06140317
Quelldatensatz	uspto-grants-2000_10
ORD ID	ord-b5fecb1b1a8d434d917ad74f33cfe993
Quellennotiz	uspto-grants-2000_10